Hematologic Disorders Associated With Deletions of Chromosome 20q:A Clinicopathologic Study of 107 Patients
نویسندگان
چکیده
منابع مشابه
Molecular Study of Partial Deletions of AZFc Region of the Y Chromosome in Infertile Men
Background & Aims: The most significant cause of infertility in men is the genetic deletion in the azoospermia factor (AZF) region that is caused by the process of intra- and inter-chromosomal homologous recombination in amplicons. Homologous recombination could also result in partial deletions in AZF region. The aim of this research was to determine the association between the partial AZFc del...
متن کاملMolecular analysis of chromosome 20q deletions associated with myeloproliferative disorders and myelodysplastic syndromes.
Acquired deletions of the long arm of chromosome 20 are found in several hematologic conditions and particularly in the myeloproliferative disorders and myelodysplastic syndromes. The spectrum of diseases associated with 20q deletions suggests that such deletions may mark the site of a tumor suppressor gene that contributes to the regulation of normal multipotent hematopoietic progenitors. We p...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 1996
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/106.5.680